Author(s):
Sahana B, Sahana M M
Email(s):
Email ID Not Available
DOI:
10.52711/jnmr.2025.31 
Address:
Sahana B1, Sahana M M2
1Assistant Lecturer Department of Nursing Foundation, JSS college of Nursing, Mysuru, Karnataka, India.
2Assistant Lecturer Medical Surgical Nursing, JSS college of Nursing Mysuru, Karnataka, India.
*Corresponding Author
Published In:
Volume - 4,
Issue - 4,
Year - 2025
ABSTRACT:
Guillain-Barré syndrome (GBS) is a serious but manageable condition. A monophasic polyradiculoneuropathy that is classically postinfectious and immune-mediated, it stands as the primary global cause of acquired neuromuscular paralysis. In many instances, the immunopathological mechanism causing nerve damage is poorly understood. The diagnosis of GBS is based on clinical characteristics, reinforced by laboratory results and electrophysiological evaluations. While once categorized into primary demyelinating or axonal forms, this division is becoming increasingly contested and is not supported by the latest European Academy of Neurology (EAN)/Peripheral Nerve Society (PNS) guidelines. Intravenous immunoglobulin and plasma exchange continue to be the main treatment methods, irrespective of the electrophysiological subtype. The majority of patients improve, but around one-third need mechanical ventilation, and 5% pass away. Currently, disease activity and treatment response are assessed through regular neurological examinations and outcome measures, while the possible role of fluid biomarkers is being continuously investigated. New possible treatments for GBS are being investigated, but none have changed clinical practice so far. This review offers an extensive update on the clinical and pathological features of GBS for both clinicians and researchers.
Cite this article:
Sahana B, Sahana M M. Case Report on Guillian-Barre Syndrome. A and V Pub Journal of Nursing and Medical Research. 2025;4(4):136-7. doi: 10.52711/jnmr.2025.31
Cite(Electronic):
Sahana B, Sahana M M. Case Report on Guillian-Barre Syndrome. A and V Pub Journal of Nursing and Medical Research. 2025;4(4):136-7. doi: 10.52711/jnmr.2025.31 Available on: https://jnmronline.com/AbstractView.aspx?PID=2025-4-4-7
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