Author(s): Ali A. Dawood, Rasha W. Salim

Email(s): aad@uomosul.edu.iq

DOI: 10.52711/jnmr.2025.26   

Address: Ali A. Dawood1*, Rasha W. Salim2
1Department of Anatomy, College of Medicine, University of Mosul, Mosul, Iraq.
2Department of Basic Science, College of Nursing, University of Mosul, Mosul, Iraq.
*Corresponding Author

Published In:   Volume - 4,      Issue - 4,     Year - 2025


ABSTRACT:
Legionella pneumophila is a water competent opportunistic pathogen which causes Legionnaires disease and other respiratory disease. In this review, the authors will look at survival strategies and mechanisms of the persistence of L. pneumophila in industrial water systems. The most important aspects of these investigations were the formation of a biofilm matrix, intracellular replication in protozoan hosts, survival under stresses imposed by the environment, and sustained exposure to disinfection measures. The resilience is associated with prolonged biphasic lifecycle, gene regulation systems and active entry into viable but non-culturable (VBNC) states. Colonization is further affected by environmental drivers which include temperature, hydraulic flow, nutrients and stagnation. The enhancement in molecular identification tool and environmentally friendly control strategies too is covered. The comprehensive knowledge of microbial ecology, environmental engineering and monitoring is a necessary prerequisite to the surveillance and the reduction of the risk of L. pneumophila in the water systems of industry.


Cite this article:
Ali A. Dawood, Rasha W. Salim. Survival Tactics of Legionella pneumophila in Industrial Water Infrastructure: A Study of Persistence and Growth Dynamics. A and V Pub Journal of Nursing and Medical Research. 2025;4(4):116-0. doi: 10.52711/jnmr.2025.26

Cite(Electronic):
Ali A. Dawood, Rasha W. Salim. Survival Tactics of Legionella pneumophila in Industrial Water Infrastructure: A Study of Persistence and Growth Dynamics. A and V Pub Journal of Nursing and Medical Research. 2025;4(4):116-0. doi: 10.52711/jnmr.2025.26   Available on: https://jnmronline.com/AbstractView.aspx?PID=2025-4-4-2


REFERENCES: 
1.    Burlingame GA, Bartrand TA. Laying the groundwork for a Legionella pneumophila risk management program for public drinking water systems. J Water Health. 2024; 22(12): 2385-2397. doi: 10.2166/wh.2024.476.
2.    Viasus D, Gaia V, Manzur-Barbur C, Carratalà J. Legionnaires' Disease: Update on Diagnosis and Treatment. Infect Dis Ther. 2022; 11(3): 973-986. doi: 10.1007/s40121-022-00635-7.
3.    La Sorda M, Palucci I, Natalini D, Fillo S, Giordani F, and Paglione F. Case report: First report of Legionella pneumophila and Bordetella bronchiseptica coinfection in an immunocompromised patient. Front Med (Lausanne). 2024 Oct 22; 11: 1470567. doi: 10.3389/fmed.2024.1470567.
4.    Wang H, Edwards M, Falkinham JO 3rd, Pruden A. Molecular survey of the occurrence of Legionella spp., Mycobacterium spp., Pseudomonas aeruginosa, and amoeba hosts in two chloraminated drinking water distribution systems. Appl Environ Microbiol. 2012; 78(17): 6285-94. doi: 10.1128/AEM.01492-12.
5.    Zhang C, Struewing I, Mistry JH, Wahman DG, Pressman J, Lu J. Legionella and other opportunistic pathogens in full-scale chloraminated municipal drinking water distribution systems. Water Res. 2021 Oct 15; 205: 117571. doi: 10.1016/ j.watres.2021.117571.
6.    Caicedo C, Rosenwinkel KH, Exner M, Verstraete W, Suchenwirth R, and Hartemann P. Legionella occurrence in municipal and industrial wastewater treatment plants and risks of reclaimed wastewater reuse: Review. Water Res. 2019 Feb 1; 149: 21-34. doi: 10.1016/j.watres.2018.10.080.
7.    Delafont V, Brouke A, Bouchon D, Moulin L, Héchard Y. Microbiome of free-living amoebae isolated from drinking water. Water Res. 2013; 47(19): 6958-65. doi: 10.1016/ j.watres.2013.07.047.
8.    Fisman DN, Lim S, Wellenius GA, Johnson C, Britz P, and Gaskins M, et al. It's not the heat, it's the humidity: wet weather increases legionellosis risk in the greater Philadelphia metropolitan area. J Infect Dis. 2005; 192(12): 2066-73. doi: 10.1086/498248.
9.    Gleason JA, Newby R, Gaynor JJ, Lee LH, Chu T, and Bliese AD, et al. Legionella monitoring results by water quality characteristics in a large public water system. Environ Sci Pollut Res Int. 2023; 30(19): 55974-55988. doi: 10.1007/s11356-023-26198-9.
10.    Lu J, Struewing I, Yelton S, Ashbolt N. Molecular survey of occurrence and quantity of Legionella spp., Mycobacterium spp., Pseudomonas aeruginosa and amoeba hosts in municipal drinking water storage tank sediments. J Appl Microbiol. 2015; 119(1): 278-88. doi: 10.1111/jam.12831.
11.    Martin RL, Harrison K, Proctor CR, Martin A, Williams K, and Pruden A, et al. Chlorine Disinfection of Legionella spp., L. pneumophila, and Acanthamoeba under Warm Water Premise Plumbing Conditions. Microorganisms. 2020; 8(9): 1452. doi: 10.3390/microorganisms8091452.
12.    Gleason JA, Cohn PD. A review of legionnaires' disease and public water systems - Scientific considerations, uncertainties and recommendations. Int J Hyg Environ Health. 2022; 240: 113906. doi: 10.1016/j.ijheh.2021.113906.
13.    Völker S, Schreiber C, Kistemann T. Modelling characteristics to predict Legionella contamination risk - Surveillance of drinking water plumbing systems and identification of risk areas. Int J Hyg Environ Health. 2016; 219(1): 101-9. doi: 10.1016/ j.ijheh.2015.09.007.
14.    Cohn PD, Gleason JA, Rudowski E, Tsai SM, Genese CA, Fagliano JA. Community outbreak of legionellosis and an environmental investigation into a community water system. Epidemiology and Infection. 2015; 143(6): 1322-1331. doi:10.1017/S0950268814001964.
15.    Buultjens AH, Chua KYL, Baines SL, Kwong J, Gao W, and Cutcher Z, et al. High-performance Legionella pneumophila source attribution using genomics-based machine learning classification. Appl Environ Microbiol. 2017; 83(21): e01482-17. doi: 10.1128/AEM.01482-17. Print 2017 Nov 1.
16.    Lombardi A, Borriello T, De Rosa E, Di Duca F, Sorrentino M, and Torre I, et al. Environmental Monitoring of Legionella in Hospitals in the Campania Region: A 5-Year Study. Int J Environ Res Public Health. 2023; 20(8): 5526. doi: 10.3390/ ijerph20085526.
17.    Dawood A. Using Remdesivir and Dexamethasone for Treatment of SARS-CoV-2 Shortens the patient's stay in the Hospital. Asi J Pharm Res. 2021; 11(2): 138-0. doi: 10.52711/2231-5691.2021.00026.
18.    Anima Biswas, Divya Pujari, Manisha Masih, Arin Bhattacharya. Anti-Microbial Evaluation of Newly Synthesized Hetero-Aryl Thiazole Derivatives. Asian Journal of Research in Chemistry. 2025; 18(4): 246-0. doi: 10.52711/0974-4150.2025.00038.
19.    Dawood A, and Jasim B. The CRISPR Genome Editing Process is an Effective Advancement of Short-Term Cancer Treatment. Res J Pha Dos Fo Tech. 2021; 13(1): 54-56. doi: 10.5958/0975-4377.2021.00009.4.
20.    Keke M, Nnanwube I, Onukwuli O. Overvew of Boleachng. Journal of Engineering Research and Reports. 2023. https:// doi.org/10.9734/jerr/2023/v25i2884.
21.    Sayqal A, Ahmed OB. Advances in Heavy Metal Bioremediation: An Overview. Hindawi Publishing Corporation. 2021. https:// doi.org/10.1155/2021/1609149.
22.    Dawood A. Reasons for discontinuing the use of Hydroxychloroquine in the treatment of the Novel Coronavirus. Asi J Pharm Ana. 2021; 11(2): 179-0. doi: 10.52711/2231-5675.2021.00030.
23.    Alhiti LS, Hamid E, Abdullah FH. Green Methods for Gold Nanoparticle Synthesis: Properties, Characterization, and Diverse Applications Review Article. Humanitarian and Natural Sciences Journal. 2025. https://doi.org/10.53796/hnsj63/12.


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